BRIEF INTRODUCTION INTO THE PROBLEM OF COVID-19 IMMUNIZATION
S protein of Covid-19 virus SARS-COV-2 is positioned too close to a black spot of
immune system where IgM antibodies live longer than IgG ones giving no heard immunity to the population,
thereby genuine S protein is not potent enough to provoke creation of effective and durable antibodies.
This is pretty similar to the smallpox situation resolved by Edward Jenner vaccine.
Genuine S protein cannot provide effective long term immunisation. It is really difficult for natural
virus to be positioned too close to the black spot, simply because Genetic Algorithm (GA) common to all
living creatures cannot converge trough areas of black spots. GA is heuristic algorithm primarily used in
optimisation of compression of computer images today, it has its limitations but nature favoured it over
all other ones and practically it is the only one driving both evolution and immune system.
Therefore the immunisation must be obtained either by similar S protein offering much
better immune response or by genetically modified virus related to SARS-COV-2 on the same way as cowpox
to smallpox in Edward Jenner vaccine.
There are three novelties based on quantum olfactory theory I proposed in the text
below:
Quantum Mirror theorem claiming that there is certain
region of IR spectrum in which this spectrum of antibodies complementary matches the spectrum of antigens
similar as positive and negative black & white images. This is very important for quickly detection
whether antibody matches antigen. For this test it is necessary possession of both antigen and antibody
in substantial quantities.
Quantum reciprocal theorem obtained by application of
quantum Bloch theorem to the Van Der Vaals bounds in proteins: if the antibody A against antigen A
affects antigen B then antibody B against antigen B will also affect antigen A. This test is very
important for quick determination whether there is trans immunity between two antigens as this is
the case with smallpox and cowpox viruses. For this test is necessary possession of both antibodies
against initial antigen and test antigens in substantial quantities.
Mild denaturation of the genuine S protein may provoke
creation of the antibodies with much wider spectrum and much more durable. The method for reversal
denaturation once awarded with Iv Nobel prize can be very beneficial for accurate level of denaturation
of be maximised both durability with wideness of the affectivity of genuine antibodies alteration, but
two my methods of denaturation might be very useful in this particular case.
By these three advances it might be possible to create effective long term vaccine
against basic Covid-19 and incoming strands too.
PREFACE
This concept of mine is simple, cheap and ready for mass production. This is
excellent first step in the suppression of this global contagion. And what is the most important
is that this is achievable in very short time, quit quickly, almost instantly. I know that there
are synthetic vaccines theoretically much better than mine one, but there are several insurmountable
advantages of my concept:
It offers long term immunity because it does not try to mimic genuine Covid-19 virus on any way,
but instead of that it tries to make immunization by viruses offering much more durably and better
immunization that also offer immunization to Covid-19 too, resembling to the situation with cowpox
vaccination against smallpox that offers much longer and efficient immunization than by genuine
smallpox virus.
It offers quick rapid creation based on existing flu vaccines that had already successfully passed
all clinical trials as major components of this vaccine of mine.
If offers well evolved methods for its production based on chicken eggs on the same way as ordinary
annual flu vaccines in immense quantities and tremendously small price with maintained constant quality
regardless quantity and these all are achievable in very short time.
This contagion will not stop by itself, i.e. spontaneously due to limited period of immunization
of population statistically and epidemiologically matching the situation with Tuberculosis, Leprosies
and Plague, but this infection has one major advantage over rest ones - it offers recovery with
optional reinfection which is quantum leap in germs' evolution. Therefore this infection can last
forever if we do not provide continuous immunization of population via permanent vaccination in
significant period of time, and this is useful only if there is no some clandestine natural or
malicious reservoir of this virus, otherwise immunization must continue forever or for very long time
with expectation that immunization will be possible with a single shot and this concept of mine offers
just that.
I do not claim that my concept of vaccine is better of the duly synthetic one which
seems to be better, but we should pay attention that production of completely synthetic vaccine on
grand scale was unsuccessful till now. The quality of such vaccine mainly depends on the degree of
purification. The quality of purification greatly depends on the production time, clearly making
sharp distinction between quality and quantity while quality of my vaccine is steady regardless the
quantity possibly offering much longer immunization with potentially more unwilling effect, practically
in the margin of ordinary annual flu vaccines.
Pleas bear in mind that Scientific progress is consisted of several steps:
absolutely first step is to ask right questions and then to find true answers on those questions, as
many as possible. After that, it should be proceeded with finding the solution to the ongoing problem.
And there are following question that demand answers:
Is the Covid-19 virus the only culprit for the
infection? If so then what is causing lung tissue damage clearly detectable by biopsies, bronchoscopes
and Rontgen imaging in state of leucopenia? How the cytokines storm can occur in the absence of
leucocytes as main source of those cytokines?
What causes chemolysis as main source of rapid
deterioration of erythrocytes similar to one in Malaria patients and microwave poisoning? As the
erythrocytes posses neither DNA or RNA they are not susceptible to viral infection of any kind and
there is very small chance that the virus itself is the cause of this rapid erythrocytes
deterioration. As we may exclude microwave radiation as the cause then this implies that whole set of
symptoms are produced by multitude causes combined and all yet to be discovered.
Why are there two period of incubation, the short one
and long one for the same virus? Are there actually two types of infection: directly from human to
human with long incubation and from vector to human with short incubation. Are the mosquitoes actual
virus vectors!? Can it be spread via meat or potable water!? There is clear connection that in
undeveloped areas without waterworks grids the number of infected is almost negligible...
Does pets and farm animals spread the infection,
especially cows, pigs and chickens!?
Is this actually a binary disease with a virus that
only instigates creation of droplets thus facilitating spreading of main germ. Why the clinical image
of smokers are milder one and is this somehow connected with the fact that tobacco is strongest
natural antimycotic?
If this is really just one very strange virus able to cause all these symptoms
combined then this simple and effective vaccine of mine will solve whole this situation otherwise it
will show that there is an extra culprit that should be treated differently and I have no doubt that
this part is much easier task than this first one. We simply do not have time for further debilitation
of world's nations by some minor technicalities and envies and therefore this is right time to start
with mass production of an quite efficient vaccine.
To stress again: this paper of mine offers generalized method for vaccines creation
on fast, cheap and pretty reliable way ready for mass production on grand scale and that this vaccine's
concept can be used for cure too and not only for protection. And there is a good chance that even the
vaccine for AIDS can be created by this concept of mine.
Abstract
The text below contains three major advantages in understanding of immunity system operation:
The first advantage is Immunity Reciprocal Theorem standing that if the antibodies against virus A
affects virus B than the antibodies against virus B will also affect virus A – and this is
Reciprocal Quantum Effect – that simple. This is going to be significant help in creation of vaccines because
extracted antibodies against e.g. Covid-19 might be used to test its action against viruses covered with existing
vaccines and if there is a suppressive effect then those vaccines will also be affective against Covid-19 virus.
This Reciprocal Effect is well known in polychrome excitations of optical receptors in eye. Immunological Quantum Effect is
identified some 15 years ago as main culprit for falsely positive serological tests where several different antibodies combined act
identically to a non-presented antigen which then trigger falsely positive identification of serological tests.
The second advantage is explanation of alleged healing of infection putatively without creation
of antibodies – simply those patients create some other sort of antibodies also able to suppress the infection which
is determined by the memories of their immune systems. Therefore absence of anticipated antibodies does not imply
missing of effective antibodies at all.
The third advantage is a mechanism of excitation to create desired antibodies by the proteins
from the area of complementary sideband. This is very important because there are animals able to produce much better
antibodies against certain infection than humans, but with such excitation we can enforce human immune system to
create same sort of antibodies which is initially impossible by exposure of humans by the particular germ. It appears
that the first vaccine ever created against Smallpox by vaccination against Cowpox is based on this Reciprocal Quantum
Theorem of mine and that it is also much more durable than immunity achieved directly by Smallpox infection with the
simple explanation – immune system much better handle Cowpox infection than Smallpox one providing much longer
immunization against Cowpox than Smallpox infection with useful side effect that this Cowpox immunization is effective
against dreadful Smallpox disease too.
Full Formal Derivation of Quantum Reciprocal Theorem of Immunity is too much complicate for this paper, but
identical reciprocity does exist in the eyesight physiology of color vision embodied in the Theorem of Colors
Similarities giving additional validity proof of Immunity Reciprocal Theorem.
Press the following button to download this article in the PDF format:
QUANTUM VACCINE
Concept of Quantum Vaccine is fairly simple and
it is based on the premise that all biological processes are ruled by the
quantum interactions and not as it is previously assumed on the genetic
shaping. This concept is instigated by C number paradox which claims that more
genome data does not create more complex creature, but only creature with
better digestion. There is also a fact that our smell sense can process smell
data within milliseconds instead of hours firmly implying that smell sense
utilizes some shortcut instead of thorough chemical analysis. This absent of
vast amount of genetic data according our expectations may have only two
explanations: DNA and RNA are not only containers of genetic data or they are
just trimming some quantum parameters that lead to shaping of our bodies,
something like functional fractal compression. If the second option is correct
one then this implies that all over the universe eventual creatures should be
mutually similar ones, but by far more important is that basic system is driven
by quantum properties, including physical senses and immune system - and
probably consciousness too. Later, about 2010, it was proven that smell sense
is based on the quantum affinity function and I assumed that my theory of
quantum operation of antibodies is more plausible that I had initially
expected. What we need right now is an established functional formalism of
immunology which is not in existence yet. Absence of this functional formalism
of immunity prevents us to have generalized method for creation of vaccines and
medicaments of every new contagion with few rare exceptions I.e. we do not have
analogy of Newtonian formalism in Classical Mechanics in immunology despite
centuries of accumulated medical knowledge.
This concept of mine simply offers a formalized
methodology to classify immune components and immune response, to sort
antibodies and antigens, to detect similarities and to rank them according
likenesses in GAM space. Now we have criterion how to classify and sort them
all, which potentially is a strong tool for vaccine creation.
The problem with generalized immune space is
that it is pervaded with blind spots and blind areas where immune system does
not respond to any antibody located in those islands of non activities and the
good reason for existence of these blind spots is that there is no expectation
that a natural germ could occur in those areas, most like those blind areas are
connected to some characteristic of aforementioned quantum compression. Therefore
it is very rare case that antigen is settled in the blind area because it is
driven by same quantum functions as ones of immune system of the host, but
occasionally these exceptions are going to happen, just like smallpox in South
America's indigene population, AIDS, etc. If the immune system is really driven
by the quantum wave function as all evidences are sustaining this hypothesis,
we may expect that every antibody has radius of efficiency and that there are two
sidebands for each antibody. But, the most important aftermath of quantum
immune reaction is that several antibodies combined my act as a single
resulting antibody. This implies too that immune system has some sort of
quantum memory which is going to be true and that this memory is not only embodied
in the variety of IgG antibodies, but also in memorized experience. It seems
that neural system also utilizes in the process of antibody creation trough
neural-immunology process utilizing brain power, which might be the mechanism
that triggers autism: brain concludes that is way much more important do deal
with immunity than to arrange environmental interaction probably by some early
multi germs infection.
This problem occurs with experimental cultivated
and humanized viruses. Whenever there is an expectation that some virus is
going to traverse from an animal to humans scientists are trying to create
virus useful for vaccine creation. Such natural virus usually is not yet fully
capable to infect people and therefore this process must be accomplished
artificially. This is standard procedure developed for seasonal flu vaccine
production. Those altered viruses may infect several species, always humans and
standard laboratory animals, usually these are always capuchin monkeys. By
cultivation the virus is debilitated and enervated and its RNA strand is
shortened by CRISPR procedure. This is done to facilitate interspecies
infection and to prevent instant extermination by the host's immune system.
Those viruses instigate host's immune system to produce effective antibodies
against initial virus, but not much effective against this modified one and
cause of this absurdity is located in theory of Quantum Resemblance. This
theory also offers a solution how to instigate creation of antibody against
this altered virus.
BRIEF INTRODUCTION INTO THE TOPIC
Immune system creates two major types of
antibodies IgG and IgM: IgM is antibody against germs of ongoing infection
while IgG is protective one. Immune system also may utilize interferon against
viruses. Every virus resembles to USB memory stick and it inserts its genetic
data trough cell's receptors. Fully developed theory of such receptors exists
only for bacteria where they are using some chunks of genetic data for
exchanging receipts how to cope with natural and artificial antibiotics - those
chunks are known as bacterial plasmids. It is interesting that a bacterium can
change its own genome in accordance with plasmid's information - quite contrary
to Darwin theory, duly favoring Lamarck's one. We have one strange phenomenon
observed in the children with disabilities: their parents started to make
multiple full genetic decoding of their children due to sudden availability and
affordability of the process and they soon realized that genome is changing
with aging which was initially explained as imperfection of decoding process.
But with advancement of this process it has appeared that those alterations are
genuine ones whose are explained by euphemism of "genes activations"
- which is actually a term explains nothing, but sounds bombastic. We may
expect that those genes activations are initiated by some sort of human
plasmids as they are receptors on human cells membrane usually assumed as
atavisms and evolutional relicts. Every single virus has several lipid layers
and those lipids fit into these sockets giving it ability to abuse several cell
receptors at once.
Interferon clogs and temporary deactivate those
receptors and usual side effect is that the cells stop their multiplications in
presence of interferon just like in case of citostatics. Therefore all viruses
are abusing already existing cell ports only, i.e. existing cell receptors.
Antiviral medicaments target either viruses themselves or appropriate receptors
on human cells. The good and also not so good fact is that human cells have
finite number of receptors which implies that there should be finite number of
antiviral medicaments for the first line of defense against all possible
viruses, ones similar to Interferons.
THE PROBLEM AND THE SOLUTION
The simplest and most truthful description of
that the crux of the problem is aforementioned lack of the formalized
functional theory of immune system able to provide method of virus sorting
according their mutual resemblance. The solution is very simple and it should
come from creation of similar formalized theory of sight as we may expect that
all human senses are driven by same quantum property, like smell, sight,
hearing, etc. We also know that neural system plays great role in creation of
antibodies by the process known as neuro-immunology. We all know that in
early stage of flue we all have reduced mental capacity and probably this is
caused by utilization of the part of our brain processing power for creation of
the antibody. This implies that brain can help and that this help is
computational. If it is so then it implies that some sort of mathematical
analysis is applied to some sort of heuristic properties of an antigen. It
means that our immune system and our brain deal with some generalized image of
the antigen trying to find best matching complementary image of antibody and
seems that whole process resembles to obtaining of complementary image in some
generalized space of immunity. The problem obviously occurs in situation when
such complementary image either does not exist at all or immune system cannot
find it. Conveniently, most of the germs are subjected to their immune
complementary images because they are shaped by the same quantum biological
processes that shaped our immune system. This implies that the problem causes the
germs created unnaturally or unfamiliarly because their complementary image
does not match them from standpoint of host's immune system. But, the pertinent
question here is whether some animal can offer more effective antibody than
human’s one and then whether we can humanize this animal antibody by adjusting
its ends of Y globulin.
SIMILARITIES BETWEEN IMMUNE RESPONSE AND PRIMARY COLORS
As aforementioned, we expect that eyesight is
driven by the same quantum function as immunity altogether with other senses
too.
My initial hypothesis was that there is
connection to the psychoacoustic model of our hearing sense, but I believe now
that psychoacoustic model rather is originated in Quantum Mechanics then in the
evolution itself. There is one strange property of the light in which blue
light passed through yellowish filter becomes white light consisted of full
spectrum colors. There is no harmonics mathematics able to handle this effect
properly, only Quantum Mechanics is duly capable to viably explain this
phenomenon.
The sight is based on recognition of three
primary reflective colors Cyan, Magenta and Yellow or three primary glowing
colors Red, Green and Blue. This ability to create every single color as
mixture of primary ones is generally assumed to be simplification done
evolution, but it appears quite recently that every single color can be effectively
created by the sum of these three primary colors and that it is possible due to
quantum property of the both solid state emitter and solid state absorber. The
diagram of absorptive CMYK and luminescent RGB colors:
Fig. 1
Color space is usually described by three
integer values from 0 to 255 or by three real values between 0 and 1 and those
three coordinates defines any color in 3D RGB space.
Primary luminescent colors are red, green and
blue and those colors are shining colors, i.e. colors of light sources. The
primary object’s colors are absorptive ones; they are cyan, magenta and yellow,
sometimes with added black k color. Those three essential colors (with added
nonessential k one) simply absorb parts of spectrum reflecting only certain
light frequencies of preferred color.
What is interesting in this concord of colors is
that blue color passed through yellowish filter yields white color with full
spectrum although the expectation is that no fraction of blue light will pass
through yellowish filter simply because yellowish filter is designed only to
absorb blue light from white one. And this will work even if we use blue laser
LE diode containing only one frequency of blue spectrum - the outcome will be
white color too. And this is modus operandi of white LE diode - the blue one is
shielded with yellowish filter giving us white light. Explanation of operation
of this conversion of monochromatic blue light into polychromatic white one is
not explainable by Fourier mathematics simply because we are mesmerized with
the L2 approximations like Least Quadrates, Fourier expansions, most
likelihood, etc., neglecting whole class of functions and expansions that are
not equidistant and not of LP norm with P equal to 2. Thereby we
came into the land of Quantum Mechanics. Directly from Quantum Mechanics theory
was derived mathematical theory of Wavelet approximations which is pretty close
to something we are trying to handle here. You can assure yourself into
abovementioned text with the one CD or DVD acting as diffraction lattice able
to decompose light to basic colors by reflection them from a smart phone with
OLED display. OLED display is actually consisted of many tiny lasers and this
can be verified with polarized sunglasses: it is obvious that the light from
OLED display is polarized indeed and there is no reason to be polarized except
it is originated in a millions of tinny lasers. Final proof is by reflection
from CD or DVD was single light strips become clearly visible. So, you can use
either a blue light diode or simply an OLED smart phone with blue screen and by
looking through yellow glasses it will show you bright white light - again
reflected from CD or DVD will expose its full continuous spectrum. This simply
implies that existence of three type of receptors in our eyes are not some sort
of simplifications done by evolution to facilitate vision processing to the
brain, but actually it is based on the quantum property of both solid state
emitter and solid state absorber. It seems that we actually can reconstruct
full spectrum from these three color coordinates only, i.e. by their intensity
arranged in RGB vector coordinate in RGB space. Just to portrait how much
Quantum Physics is ruling our world let us peek to Newtonian cradle:
Fig. 2
Newtonian cradle is consisted of several rigid
balls that demonstrate transfer of impulse trough them. If one side ball (blue
one) is pulled and released then the last one (green one) will jump out. Naive
analysis via Classical Mechanical laws of energy and momentum conservations
yields that last ball has to jump out and recoil of penultimate one. The problem
is that these middle balls (orange ones) are not moving at all according these
two conservation laws and yet last one is able to recoil from penultimate one
duly at rest. This is pertinent place for the vivid question - what passed
through middle balls that is able to carry both linear momentum (i.e. impulse)
and energy causing last one to jump out. Only application of quantum
Kronig-Penney phonons flux to this pendulum is able to give profound
explanation of the conundrum embodied in this pendulum. This also could be the
explanation of sonic levitation too. This is pretty compelling evidence of
Quantum Mechanics validity, and we will use it in an attempt to classify and
sort antigens.
The existence of such
color space gives us ability to establish criterion of similarity between two
colors. The basic criterion of color similarities should be angle θ.
Therefore we may consider two colors similar regardless their mutual
intensities if the angle between their vectors in RGB space is small enough. Angle
θ between two color vectors in RGB space is:
(1)
If angle θ is smaller than some predefined
criterion then two colors are similar. This is very important conclusion about
similarities between vectors, in this case these are vectors of two colors in
RGB space, but if we may compare two or more colors by the criterion
established with above equation then we should be able to compare antigens and
antibodies on the same way too, on properly established coordinate system of
immunity space.
The only theory able to provide any solid explanation
of immune system operation is Quantum Mechanics, just because it offers a
criterion of quantum resemblance which can be utilized in classification and
sorting of germs from the standpoint of immune system's resemblance.
There is one tantalizing
hypothesis of mine developed during 2007 based on the hypothesis that immune
system operates on the same way as smell sense and we may assume that eyesight
also operates in color recognition on the same way as smell sense. This
hypothesis tells us two things: those energy levels are basis of similarity
criterion and that selectivity of antibodies are not perfect implying that
there is a perimeter of their effectiveness. According theory of Quantum Supper
Lattice it is possible to moderate effective properties of a material simply by
supper lattice compound of two distinctive materials layers creating preferred quantum
response, just as there is a new resulting homogenous material interacting with
electromagnetic radiation on the same way as supper-lattice. According analogy
this means that properly chosen several antibodies will yield combined response
as there is a single antibody. There are two options to treat this situation
with Quantum Mechanics. One is approximation by the series of WBK
approximations, and WBK approximation is actually probability of the particle
to tunnel potential barrier:
(2)
Abovementioned method yields very good
quantitative explanation of the white light from blue source and yellowish
filter.
For several barriers
the convergent chain of probabilities can be established. But, we can rely on Supper Lattice
and Block Quantum Theorem too for dz2<<θ:
(3)
According analogy with the eyesight and
similarities with the colors we know that two colors in RGB space are similar
regardless their intensity if the angle between RGB vectors are small enough
within preset criterion of similarity as it is explained in above text.
This practically means that we may establish
infra red set of colors, i.e. to divide IR band into several sub bands and to
treat these bands as colors and then to sort them via similarity of angle
between their color vectors. The catch is that the bands cannot be chosen
randomly, but they should fit into the Quantum Mechanics spectrum bands
definition, roughly defined by above equation, and those bands should match the
scales of energy levels of chemical reactions between proteins usually measured
in electron-volts or just volts with assumed electron. Although it seems to be
farfetched concept, it is not that taut as it might be seen at the glance
simply because both smell sense and eyesight operate on same quantum way.
This should be a generalized theory of
operation, i.e. modus operandi of our immune system, corresponding to Newtonian
one in Classical Mechanics and its main achievement is to categorize germs not
according their symptoms, but according their peculiarities seen by immune
system itself. This may provide us a great help in future vaccines designs and
also to expose some hidden properties of the germs too.
Our immune system resembles to leopard leather
with many black spots in which it does not react to antigen at all, but those
spots are not that dangerous simply because it is difficult for antigens to
reach those area too. Occasionally they rich those areas causing real
devastation as it was the case with smallpox in medieval period causing
majority of population to eradicate this black spot on the infected regions.
Situation became extremely difficult for South American indigenes that died in
the vast quantity practically leaving us without proper historical records of
this period before Columbus arrival. Usually pathogen has one unique signature
which facilitates immune system to cope with it, but sometimes pathogen is
similar to several ones making its identification of immune system quite
difficult, but this does not exclude successful immune response. On the figure
below is depicted situation of the antigen located in the black spot, i.e.
blind area of immune system and three antigens created by vaccines A, B and C
surrounding this area. If the antigen is located into the region close enough
to effective quantum range of antibodies created by those vaccines then it will
be attacked and successfully eliminated by those antibodies.
The image below depicts three antibodies with
their perimeters of effectiveness created by vaccines A, B and C and an antigen
supposedly Covid-19:
Fig. 3
This image, but just
without vaccines B and C portraits the first ever created vaccine by Edward Jenner
that was designed to protect specifically against smallpox. It utilized enervated
viruses of much milder Cowpox disease with virus akin to Smallpox disease able
to induce set of antibodies close enough in generalized immune space to affect
the smallpox viruses too and to deactivate them all with IgG antibodies.
The main benefit obtained from this quantum
theory of immunity is Reciprocal Theorem of Quantum Mutual Action that states:
if there are two viruses and we possess antibodies of one virus then we may
check whether this antibodies can affect another akin virus and if they can affect
it then this implies that antibodies created by this akin virus will also
affect genuine one. Translated to plain English it means that we may use
extracted Covid-19 antibodies to check whether they can affect akin viruses and
if they can do that then cocktail of vaccines for those viruses can be used in
polyvalent vaccine against Covid-19. This is Reciprocity Theorem of Quantum Immune
Mutual Action of antibodies and it follows directly from the Quantum Effective Ranges of Antibody's in generalized Immunity Space. This formal proof
is beyond the scope of this article intentionally devoted of too much
mathematics, physics and chemistry.
This concept is especially promising in case of
viruses with extremely short living antibodies, like it is the case with
Covid-19 whose half-life antibodies drop from 7.5% to 12% weekly depending on
the particular patient. In that case we may choose some akin virus able to
provoke creating of antibodies similar enough to ones of Covid-19 and effective
on it too, but much more persistent, just as it is the case with Edward Jenner
vaccine. Smallpox disease does not provide lifetime immunity, but Jenner's
vaccine does do that simply because immune system creates permanent immunity
against cowpox and just temporary one against much more severe smallpox! Even
more, we may utilize new cocktail vaccine by combining already available
vaccines in case that there are several ones already available that target
similar virus.
ANTIBODIES AND NON SPECIFIC IMMUNE RESPONSE
The antibody immune response belongs to specific
immune response. There was speculated for quite some time that there is also a
non-specific immune response in humans too and this response has been indeed
discovered recently. Non-specific response is based on creation of the
substance corresponding to natural antibiotic aimed to act against broad
spectrum of germs. Those substances has been recently discovered in case of
some parasitic infection and very few bacteria and it seems that it is not
particularly effective as one in the case of insects, frogs and some herbs.
But, this scientifically neglected mechanism can explain healing of some
diseases without synthesis of antibodies in significant quantities at all. I
suppose that interferon can be assigned to non-specific immune response to
viruses too as it is natural substance with aim to deactivate certain cell
receptors and thereby to prevent cells' virus infection.
As aforementioned, there are two major types of
antibodies, the IgG and IgM ones. The IgG type is the one dedicated to protect
organism against already experienced infection while IgM type is designated to
cope with ongoing infection. The basic role of vaccines is to provoke synthesis
of IgG antibodies. Dead vaccines, i.e. deactivated ones almost always instigate
creation of IgG antibodies, while alive vaccines, i.e. enervated ones, can
create both IgG and IgM antibodies and those IgM antibodies can inflict severe
damage to persons recently experienced the disease they have been vaccinated
on, therefore the goal is to provoke creation of as many IgG antibodies with
minimal amount of IgM antibodies. The basic objective of vaccines is prevention
and not healing, although some vaccines are administrated as medicaments after
the infection, as it is case with rabies disease. The idea is provoking
creation of IgG antibodies before massive virus replication. Maybe idea to
provoke creation of IgM antibodies is not that good just because in that case
this vaccine could be considered as medicament too. Some antigens provoke
creation of persistent antibodies presented in entire lifespan after infection,
but some of them provoke creation of antibodies shortly available.
Humans are quite different than all other
mammals on many strange ways, and maybe lipid-soluble barrier is the strangest
one: this barrier prevent passage of all substances that are not soluble in
fats to the certain areas of our bodies, like brain, eyes and gender glands.
The existence of this barrier seems to be detrimental for us, e.g. our brain
cannot consume anything else but glucoses although it fully utilizes aerobic
Krebs cycle contrary to anaerobic Cori cycle strictly limited to glucoses
consumption too but its metabolic product is either acid or alcohol. Cori cycle
is our native metabolic cycle embedded in our indigene DNA strand while Krebs
cycle is located in mitochondrial DNA inherited only by mother's side settled
outside main DNA. It is pertinent place to be mentioned that metabolism of
cancer cells is devoted of Krebs cycle therefore fully relying on ineffective
Cori cycle only, which is peculiar trait utilized for cancer detection in PET
tomography for last 40 years. Also, most of single cell parasites like yeasts,
funguses and amoebas also utilize exclusively the Cori cycle, too. Both cancer
cells and funguses are protecting themselves from immune system by the layer of
chitin in their cellular wall. It is interesting that there is no code for
chitin synthesis in our genome and somehow cancer cells can do that despite
missing genetic instruction.
Very good Chloramphenicol antibiotic significant
in veterinary medicine is toxic for humans due to lipid-soluble barrier. This
barrier also prevents our antibodies to reach our brain, our eyes and our
gender glands in enough quantities giving a chance for some viruses to remain
in those areas for quite some time. If the inappropriate vaccine is
administrated to such convalescent the very detrimental effects can appear,
even to cause disabilities like temporary or permanent blindness, sterility or
brain damage. It was occasional case with smallpox mass vaccination in former
Yugoslavia in 1972 with several hundred blinded people that already had asymptomatic
smallpox infection prior the vaccination. This situation was duly clarified
with recent Ebola vaccine allegedly causing sterility to certain number of
African women implying that even Ebola could have asymptomatic cases in much
higher quantity that it was previously assumed.
SPECIALIZATION OF IMMUNE SYSTEM
Immune system has several major branches of
leucocytes, i.e. White Blood Cells (WBC) according their particular
specialties. Neutrophils are dedicated to cope with bacteria, eosinophils are
specialized against parasites and cancer cells and usually they release
citocines, basophils are also dedicated to cope with cancers, infections and
ionized radiation exposure and monocytes are specialized to fight viruses and
some single cell parasites, lymphocytes are dedicated to suppress most viral
infections, very few bacterial infections and some cancers. Demand for instant
massive production of a specific branch of leukocytes in ongoing infection
always causes drop in productions of all other branches of leucocytes usually
leaving patients susceptible to opportune infections. We should bear in mind
that we have vast amount of so called good bacteria in our bowel system and
they are good only because our immune system keeps on them and temporary
elimination of those bacteria is the great relief for our immune system during
ongoing viral or fungal infection. Therefore giving antibiotics to patients
with viral infections might be circumstantially quite beneficial despite the
fact that antibiotics are not killing viruses, but they are giving chances to
those patients to boost their antiviral immune resources safely. They are
constant fight of doctors against routine prescribing of antibiotics to
preserve their efficiency in life threatening medical conditions, and I presume
that this is a bad decision: idea that somebody's organism has to cope with
bacteria with prolonged time is especially detrimental for children, limiting
their growth and retarding the development of mental capabilities, also giving
a chance for the disease to become chronic one. There is no excuse for
pharmaceutical industry in their absence of new antibiotics: we need new
antibiotics rather than to develop some masochistic fakir medical skills,
although we might consider this as sadistic too as the doctors usually decide
in behalf of us whether we should receive antibiotic or not.
ANTIBODY'S DUALISM AND QUANTUM MECHANICS
According wave function
of Quantum Mechanics, usually known as Schrodinger equation, and Quantum
Chemistry every antigen's vector in the generalized space of immunity has its
complementary vector that induces creation of identical antibody. This is
because mathematical Z transformation applied to Schrodinger wave function
always yields two side bands. Schrodinger equation is:
(4)
Although the immune reaction is not a stationary
process, we may approximate it as periodical stationary process appearing on
certain resonance only, which defines energies of protein-protein reactions.
This duality of sidebands is property of all periodical functions and it is
well known in the telecommunication where one band is desired one while other
on is eliminated by proper filtration. We can utilize this fact to provoke
immune system to create antibody even if the antigen is settled in the black
area of immune system's blindness by administration of the complementary
antigen of the preferred antibody initially unable to instigate mass antibodies
production. This is a real effect although there is no vaccine utilizing this
quantum effect yet, but this can be changed quickly. This effect might be used
in design of Covis-19 vaccine too.
This situation is explained by the following
image:
Fig. 4
There is a question whether antibodies obtained
on this way is more durable than ones obtained by the genuine Covid-19 viruses
and the proper answer is - no. Both sidebands provoke creation of identical
antibody. Above image depicts situation in which every single antibody has two
cones of actions in generalized immune space and if the immune system is
excited by the antigen in the unnatural left sideband it will create antibodies
identical to one as provoked by real Covid-19 virus in right cone, in much
bigger quantity, but with the same short time durability. This approach gives
us chance to instigate antibodies creation, but not to manage its quality.
We should notice that we are dealing here with
one continuous range of frequencies separated into several bands and that those
bands have some unique features. We may assume that this is E1
space, but actually it is not the case because those frequencies from different
bands can appear simultaneously combining features of various bands,
practically creating reaction in En space, whereas n is number of
frequency bands, i.e. number of dimensions of generalized space. This is very
important conclusion in designing of exciting proteins because these features
are reflected in the infrared spectrum of those proteins. This technological
engineering supported with proper CUDA personal computer should be an
attainable task accomplishable in quite finite time. We should bear in mind
that there is a strange ability of every single atom to emit and absorb
wavelength 5000 times bigger than its own size. This slightly aggravates exact
experimental identification of infrared spectrum of Covid-19 virus requiring whole
cluster of this virus for spectrum analysis. But, according Quantum Mechanics
the infrared spectrum can be recreated by ultraviolet one with pretty high
accuracy. This so called Phenomenon 5000 was huge challenge for me for quite
some time, I found viable explanation for this phenomenon, but it is beyond the
scope of this article. This phenomenon is usually hidden from students because
it allegedly violates basic presumptions of Quantum Mechanics, which is not
true at all, furthermore this effect effectively proves Quantum Mechanics, but
it also proves that a quantum wave package is not just an abstract packet
determined in space and time with its abstract integer quantum numbers, but
also with some real extra parameters too.
Once upon a time, around year of 2000, there was
a global initiative to support creation of those anticancer immune response
exciting proteins by installation of screen saver that had to perform such
calculations in personal computers' idle time. This initiative failed because
the theoretical concept was not evolved enough yielding very complicate
equations and due to lack of computer power too even distributed to plethora of
personal computers. We now have both computers’ power embodied in CUDA
graphical cards and we are supported by excellent approximations that
tremendously speed up this calculation just with modest decrease in accuracy.
The conclusion is that excitation of
complementary sideband region might be more lavish only, but the essential
quality of antibodies will be identical to ones obtained by excitation of
direct sideband with genuine antigen.
The crux of this problem is necessity to combine
experts from various scientific fields which seems to become impossible
endeavor these days. Google experts are not capable to make solution because
they can find on Internet something that does not exist yet. In theory we do
not need the viruses at all, or their parts, all we need is just a protein able
to mimic this viral protein's envelope.
In the case of Covid-19 contagion there are
perceivable several problems: once established alleged truth by prominent
experts is very difficult to be replaced with posterior correct one because
experts are covering each other carefully watching not to mutually contradict.
This practically eliminates any brainstorming dispute limiting chance to
properly identify true nature of the germ and the rule of contagion spreading
too, especially in case of this zoonotic pathogen. It is interesting that
epidemiological studies all over the world did not take into account whether
patients had pets or not and what they had eaten prior the infection. Way too
much versatile leukocyte formulas of different patients implies that
accumulated memory of immune system plays major role in the prognosis of the
disease - whether it will be mild fever or lethal pneumonia with severely
damaged lung tissues, this only depends on earlier immune system experience. It
seems that prior BSG vaccine is especially beneficial for Covid-19 patients,
which is pretty obvious in the countries' pair of Portugal and Spain, or East Germany and West Germany regions. It seems that smokers have better prognosis in
Covid-19, probably due to strong antimicotic properties of tobacco, which may
reveal the true nature of this germ.
As aforementioned, the major problem with the
Covid-19 virus is that human immune response is heavily relied on accumulated
experience of immune system of every single individual, rising a question
whether the immune response is unique, i.e. whether the synthesized antibodies
are the same in all humans or they varies according the memory of immune system
and therefore the most reliable test is PCR one that detect virus itself
instead of detecting of supposed specific antibodies. If somebody does not
contain specific antibodies it does not instantly mean that they does not
possess effective anti Covid-19 antibody of any kind, they does not possess
only assumed antibody, but as we saw there is no necessarily a unique antibody
for a particular virus, the whole gamut of specific antibodies can cope with
the specific virus.
The surges in number of infected people imply
that some sort of delicate conspiracy in indeed involved into the Covid-19
contagion.
ANTIBODIES AND NON-UNIQUE IMMUNE RESPONSE
Researches are quite often confused with the
fact that there is missing of expecting antibodies for the certain virus
assuming that maybe antibodies do not play major role in defense against
particular virus, but most likely this is not the case at all. Such virus
simply does not instigate creation of unique antibody to all humans and created
antibody heavily depends on the previous experience of the immune system of the
host, i.e. patient. Synthetic artificial viruses are purposely created to be
located near aforementioned black areas in generalized space of immunity to
facilitate zoonotic abilities of the new virus. As aforementioned, the main
purpose of such alteration of genetic code of genuine virus is to make virus
capable to infect multitude of animals, especially standard laboratory ones.
And this technique is well elaborated and practically in routine usage today.
This kind of virus alteration is applied on annual basis whenever there is a
perception that a certain animal virus has tendency to pass on humans and in
that case an artificial human compatible virus is going to be created to
utilize vaccine production. In that case when the virus eventually finds
natural way to infect humans the vaccine is already prepared and ready for
application. Usually, annual flue virus passes to humans either from birds or
farm animals.
Eventual immune response on the viruses located
in the vicinity of blind areas must be heavily relied on the accumulated immune
memory of the host and the utmost importance should be an effort to find beneficial
experienced events, like vaccines or previous infections, etc. Therefore any
such virus does not instigate creation of the unique antibody identical to all
humans, making most of the serology tests useless for great portion of people
and also identifying most of patients falsely negative, practically leaving
only PCR test as reliable one. Before conclusion that there is an unspecific
immune response on such pathogen it will be nice to check whether some other
kind of antibodies has been already created, maybe more effective than supposed
ones, i.e. instead of unspecific immune response maybe there is non-unique
immune response? We also may suppose that some animals can produce much more
effective antibodies and that we may humanize them via alteration of Y globulin
ends to reduce anaphylactic reactions and to improve durability of such
antibodies in the human system.
BACTERIA, VIRUSES, PARASITES AND HUMAN CELL RECEPTORS
This topic is very important because it explains
how it is possible to identify bacterium as virus. For the better understanding
crux of the problem let us pass through the brief introduction into the
replication and infection mechanism of viruses.
We may assume viruses as flash memory stick
completely devoted of any processing capabilities at all, while bacteria and
single cell parasites may be compared with smart cards supplied with full or
limited ability of data processing.
Any virus abuses the host cells receptors and
any cell has finite number of such receptors, for whose we me assume they
correspond to USB data ports. This finite number of receptors implies that
there is finite number of medicament able to fight against all viruses on the
first line of defense.
Official explanation of those receptors is
pretty confusing, and only valid explanation exists in the reign of bacteria. A
donor bacterium can exchange its positive experience in ongoing battle with
environmental threats via small chunks of RNA data and recipient bacterium can
change its own DNA dataset by reversal transcription in accordance with the
received instructions in this small chunk of RNA data, i.e. by inserting
plasmid into its own RNA strand, which is official explanation how they can so
quickly adapt to new antibiotics. Officially, anything similar does not exist
in any other species and the best guess is that human cell receptors are mainly
remnants of the evolutional past, which surely is not true at all. So, why they
are so meticulously suppressing information that human cells can change their
genetic data during lifespan!? Simply, because it thoroughly ruins Darwin's
Theory of Evolution in favor of Lamarck's one. This enforced preservation of
Darwin theory severely limits progress in our understanding of infections. There is a
pretty solid proof that they are human equivalents of bacterial plasmids
euphemistically called Activations of Genes. Actually, parents of children with
special needs recently have been performing successive full DNA decoding of
their children due to the sudden affordable widespread availability of the
decoding of entire human genome process and they noticed that there are small
differences between consecutive decoding, which is lexicographically named as
Genes Activation, but actually this is genetic alteration that simultaneously occurs
in the majority of human cells. Initial assumption was that human cells
mutually communicate via ultraviolet signals because one such signal is really
detected for cell's apotheosis, i.e. self destruction, which is indeed one UV
flare quite similar to one of sunlight, giving pretty good explanation for the
detrimental effect of sunlight to the human skin that instigates aging. It
seems that humans in the past had not been initially exposed to the UV
radiation from Sun either by different sunlight spectrum or by some sort of
atmospheric shielding probably consisted of vast amount of humidity in
atmosphere. But, the vast varieties of intricate intra-cells communications
implies that there must be some much more intense way of communication based on
direct exchange of genetic data identical to one of bacteria. Even more, in
bacterial world there are bacteriofags that directly correspond to the human
viruses by abusing those bacterial cell’s receptors initially utilized by the
bacterial plasmids. Interferons are natural substances excreted by human immune
system with the goal to clog, i.e. temporary inactivate those human cell's
receptors. If those receptors would be really just atavisms of evolution then
their inactivation should not be detrimental at all, only beneficial - but,
actually it is not the case. Cells stop to replicate themselves in presence of
interferon and this interferon's action is pretty close to citostatics and some
of interferons are indeed beneficial in cancer cures too. For me these have been
pretty solid arguments for the assumption that there must be human plasmids in
functional existence and that viruses just abuse these cells communicational
mechanism dedicated initially to human plasmids.
We may continue to make parallelism with the computers
assuming that those chunks of data embodied either in the viruses or human
plasmids must be rather coded rather in some sort of genetic script language
than into direct machine coded DNA language which is only explanation for the
existence of zoonotic diseases - there must be an universal script genetic
language for several structural DNA types. We commonly assume that we are akin
to apes, but Genetics as science states that it is not quite true: apes have 48
chromosomes while we have only 46 ones preventing us to make common fertile
offspring, but the major issue is that apes chromosomes are much bigger making
ratio between active and junk DNA much worse in respect to humans. Active DNA
is spatially located on the surface of chromosomes while junk DNA populates
interior of chromosome's hank made of DNA strand. This makes cells'
replications extremely intricate process in which entire strand mush be winded
on the same identical way and there are some attach points facilitating this
process which is located on irregular length making genetic diseases pretty
rare in apes contrary to humans because ratio of junk DNA is much smaller than
in apes with much less irregular lengths between attach points vastly
increasing chance for wrong packing. The objective of the replication is to set
active DNA always on the surface properly addressable while junk DNA is always
located inside the chromosomes and their spatial disposition must be exact the
same otherwise proper addressing of genes is impossible instantly causing
genetic disease. As aforementioned active DNA must be stored on the surface and
be properly addressable to be reachable for particular transcriptase, i.e. for
copping of parts of main DNA into RNA strand for later running of this code in
cell's alveoli. This gene addressing on the surface of chromosomes corresponds
to the program counter in computer assembly language. All chromosomes are
consisted of a single DNA strand and there are two such strands inherited from
both parents, therefore human genome is consisted of only two DNA
macromolecules. Exchanging the data between those strands is known as
Crossing-Over process. Those strands are not of same size, the one inherited
from the father is shorter due to smaller Y chromosome in respect to mother’s X
one, but these is superseded by functionality coded in X chromosome inherited
from the mother. Males do not have redundancy in both X and Y chromosomes
making them much more vulnerable to genetic diseases. Puzzling fact is that
junk DNA data has statistical distribution similar to one of alive human
language, but recent genetic experiments indeed showed that junk DNA does not
play any role in the cells' operation while their replacement with anything
else of the same data size does not affect cell's metabolism at all. It is
enigma what is written in this DNA in case it is indeed some text in any
language, user manual, service manual, copyright certificate or whatever else.
If this sort of genetic data is not useful for us then for whom it should be
useful for!? Obviously these data are meaningful to someone, otherwise it
wasn't be protected by ECC too just as Active DNA Code.
According everything abovementioned, for
thorough creation of a synthetic virus the profound knowledge of function of
entire human cell is absolutely mandatory including operation of human plasmids
that officially are not yet recognized as real items by contemporary science.
What we can do right now is to use parts of genetic data of decoded, i.e.
disassembled viruses as generic library routines that can be arranged and
combined into new synthetic virus without profound understanding of the action
of particular RNA or DNA segments, which should be attainable task in case of
single strand viruses equipped with no ECC capability. This is one very
intensive task requiring a lot of man-hours because it requires lot of
error-and-try attempts. Therefore creation of a synthetic virus requires a lot
of man-hours, or involvement of many researchers making this pretty huge and
expensive endeavor.
VIRUSES RECOMBINATION
We can also combine different viruses without
usage of expensive and advance instrumentation at all: there is a strange
natural process of viruses’ mutual recombination embodied in the ability of
akin viruses to exchange their genetic code and to make third virus, something
like viruses crossing-over. Official explanation why Covid-19 cannot infect
bats is that genuine virus was originated in bats, but it infected an animal
already infected with some human Corona virus and that in this biological host
allegedly located on green market in Wuhan appeared Covid-19 virus able to
infect both humans, dogs, cats, elephants, but not originating bats. I am not
that sure that Covid-19 cannot infect bats because it is also a viable explanation
of waves in Covid-19 contagion, possibly originated in non-human hosts via
chain bats-birds-humans. This scientific explanation resembles pretty much to
the putatively natural origin of Oklo geological nuclear reactor in Gabon,
which is so much impossible for anybody supplied even with superficial knowledge of
nuclear reactors. It seems that we need a faith in purest form to embrace
modern science, which somehow matches full scale definition of religious dogma.
What we know for sure is that there is viral recombination process in wildness
and that this is a basic generator of novel viruses. This ability of viruses to
recombine themselves, i.e. to severely exchange their genetic code to the level
of new virus creation betokens that DNA is much more than a simple data
molecular storing device. It seems that DNA and RNA are rather some sort of
materialized mathematical functions obeyed to quantum rules than being purely
data storage corresponding to USB memory sticks. This might be very useful
observation that is going to limit possible set of antigens a lot: we just
should identify this function and those rules of recombination to cover most of
antigens if not all ones. This is going to be quite attainable objective with
the aid of CUDA or similar technology equipped personal computer.
Therefore it seems that the basic mechanism of
false identification of a bacterium as a virus is misidentification of a
bacterial plasmid as single strand RNA virus and in that case some Corona virus
is going to be first choice as misidentified single stranded RNA virus. It is
pertinent place for the question: whether leprosies and plague would be
identified as viral diseases if they would be discovered today!? It is
interesting that plague convalescents can daze most of serological test and
even few PCR ones to falsely identify this bacterial disease as viral AIDS. We
are considering AIDS as viral disease while plague is going to be bacterial one
and yet a bacterial disease can confuse both serological and genetic tests of
viral disease. This requires more profound analysis of this ongoing issue
affecting contemporary scientific community, embodied in the fact that it is
still more important who said than what is said.
SCIENCE AND RELIGIONS
There are several esoteric fraternities whose
theologies are mainly based on the concept of reincarnation and pantheism, and
Darwin's theory gives them excuse for abusing rest of us as prosperity of best
fitting, which is not correct concept either by the mathematical game theory or
by evidential facts collected from the wideness. Darwin's theory offers pretty
good way to exclude the God from the equation and to vindicate cruelty, and we
will discuss in the text below whether God has to exist from the standpoint of
solid science or not! This is very important at the moment because it is pretty
obvious that those spurious theological concepts are suppressing further
technical, technological and scientific progress which is quite obvious on the
subject of Covid-19 vaccine and proper medicament. We may expect that the
objective of the economy should b fulfilling of the human needs and major
condition of any human to have needs is to be alive and therefore medicine
should be the most reliable science, but it is not the case at all. And there
are two explanations for this: the already existing self-repairing in humans
facilitates intrusion of careerists into this respectable occupation or economy
does not serve to humans. Allegedly huge amount of some products are routinely
destroyed to preserve price on market, but the locations of the places where
this destruction is going on remain undetectable and this is pretty huge task
because in case of some product it reaches almost 40%. It is pertinent place to
recall bloodletting highly detrimental procedure that had been performed for
centuries even on wounded solders with copious bleeding. This obviously highly
noxious procedure was so persistent in routine medical practice really
challenging ability of science to make conclusions over experiences and there
must be some clandestine reason for that diabolic distortion of science.
This hidden religious problem is not embodied
only in the twisting, bending and distorting of current science to remain
harmonized with some clandestine religious concepts, but also they are
violating social law of positive selection. In an ideal world every single
individual should progress till the limit of their own incompetence, but in
real world they progresses till the limit of power of their group of interest
which is usually ethnically, esoterically, religious or politically oriented
group of economical influence. This is pretty good explanation for the numerous
incompetent "Yes" men ruling our world, usually on not so exposed
positions though very important ones. They always prosecute all proficient
people simply because such people may endanger their followers making them
funny in comparison even by the eyes of a layman.
Let us pass trough solid scientific facts favoring God's existence:
Biological proof: Luis Pasteur biogenesis
rule claims that living thing appears only from another alive thing while dead
thing can appear from both alive and dead thing and with the aid of Logical
Induction we may conclude that there must be some primordial super alive being
that started to spread life in our universe or at least on our planet. My own
conclusion is that first started non biogenic, i.e. non material life that
initially appeared in plasma of stars. In plasma photons may mutually interact
giving them ability to create complex structures, possibly primordial life in
light, although CERN claims that its researchers discovered mutual scattering
of photons despite the Pauli Exclusion Principle and extremely accurate
Fermi-Dirac and Bose-Einstein distributions in its ATLAS machinery. For plasma
photon-photon interaction is fact, but for vacuum I am not that sure simply
because it implies strong non-linearity of vacuum that is purest form of
space-time fabric expected to be duly linear subject which is the fact used for
derivation of both Bose-Einstein and Fermi-Dirac distributions, almost
perfectly accurate ones.
Medical genetic proof: genetic code
is non-evolutional and identical to all leaving creature, all genetic letters
are identical and all genetic rules are identical. This implies according
logical recursion that somebody defined the rule of life's game before the game
started quite similar to chess game: the rules are already defined before the
chess game starts. The statement is further supported with existence of Error
Correction Code almost identical to MNP one applied in Fax communication or
similar to ones of CD and DVD media. There are some extra genetic data used for
error correction information. There is no explanation of gradual improvement of
sequential algorithm like Error Correction Code one. This algorithm is also
identical to all leaving creatures possessing it. There are also a genetic
decision and genetic search algorithms whose seems they are not subjected to
evolutionary changes at all, and the explanation is very simple: it is either
functional or not functional and in case of malfunction the cells die. Genetic
algorithms can be extremely parallelized, but they are still sequential ones
distributed into multiple threads. Probably there is also a recombination genetic
algorithm too, explaining viruses recombination.
Logical proof: Gödel God's Theorem
states that any set of theorems must be based on at least one initial axiom
that cannot be proven by the current set of theorems requiring external
explanations. Applied to life it consequently states that there must be some
initial factor we use to call God. The theorem is also known as Gödel's Incompleteness
Theorems
Mathematical proof: uniqueness of
Banach algebraic point states that there is only one unique Banach algebraic
point claiming that in reverse every convergence started from single point.
This further implies that eventual evolution must started from initial point
containing the same evolutionary property necessary for the start of the
convergence and to rule it further.
Philosophical proof: Thomas Aquinas
philosophically derived necessity of the existence of Absolute Observer that
gives the persistence of existence to all matter in universe even in the
absence of local observers. This means that our room does exist even if we do
not watch it because absolute observer watches on all us permanently. His
explanation was so well derived and he also predicted avitaminosis diseases
including claiming that premature aging in respect to antediluvian times is caused
by the absence of a vitamin primarily available in the gigantic Trees of Life
that did not survive global deluge. He stated that this physical explanation is
rather correct than the metaphysical theological one. This proof assume
existence of vitamins too some 600 hundred years before discovery any vitamin
at all.
Physical proof: if there are
physical laws then there must be somebody watching on these laws to assure they
are obeying to them in this universe. If there is somebody that are watching on
them than they must have its limitation and interestingly there is such
limitation below the size where fluctuation of vacuum started, which is
embodied in Casimir effect, and this is space-time volume of h3,
where h is Heisenberg constant. Holly trinity is usually explained by natural
philosophers as 0, 1 and a rule, which should be enough to define game of life
in our universe, the four major magic elements air, water, earth and fire is
usually explained as four states of matter, i.e. gaseous, liquid, solid and
plasma respectively. In the computer array game of life some rules are indeed
assumed, but the final proof remains inconclusive.
According all six major proofs we may assume
that God does exist, but lingering question is whether He pays attention to us
as units or not. As Christian I personally do belie that there is a living God
that cares about us.
Therefore there is no reason for those secret
fraternities to continue twisting science to maintain its harmonization with
their own religious doctrines. True religion does not require intervention to
be truthful and harmonized with nature because eventually it will be shown that
science was wrong and not religion if it really comes from God because God as
architect of everything visible and invisible must know the truth without
viable motif to lie his disciples.
So, there is a God as an initial point, and yes
there is an ongoing evolution, rather Lamarck than Darwin one, simply because
Lamarck evolution should be next step of evolutional improvement of initial Darwin's one.
The major question is whether this evolution is limited or it is unlimited.
If there is Lamarck evolution roaming on the stage then there must be human
plasmids and potential whole new gamut of medicaments for treatment of
infective diseases.
COVID-19 CONSPIRACY
According all aforementioned it should be
relatively simple task to create both vaccine and animal humanized serum for
Covid-19 virus. Let us recall the following facts about smallpox contagion in
Yugoslavia during 1972: in those times there were available serological tests, both vaccine
and serum obtained from the horses exposed to inactivated smallpox viruses, and
it was half century ago. The harvested animal antibodies were subjected to
process of humanization in which molecular ends of animal Y globulins were
replaced with human ones to reduce anaphylactic and allergic reactions to the
serum. And, what we have today, except the quarantine!? Is quarantine the best
medication we can figure today!? What does block current science to act
properly and to find vaccine, serum or medicament!?
It seems that Covid-19 contagion is shrouded in
many conspiracies. Statistical filtration of affirmed Covid-19 patients showed
no distinctive signature in blood leukocyte formulas. Statistical filtration is
routinely used in annual estimation of number of seasonal flue patients to
distinguish other influences from current annual flue contagion. This is based
on statistical patterns or sometimes on attractor's trajectories. This does not
imply that there is no Covid-19 contagion. The contagion is real and the dying
people are real too, and also the germ itself is real too. The initial
assumption that anti-malaria drugs might be useful came from the similarities
in clinical symptoms of Covid-19 and Malaria followed by similar statistical
irregularities in blood picture and similar hemolysis that occurs in some
Covid-19 patients. What we know till now is that in some patients occur sever
damage of lung tissue too. Official explanation is that this extensive and
often lethal damage of lungs in those patients is caused by cytokine storm, but
somehow in those cases is presented leucopenia too which excludes appearance of
cytokine storm.
It is pertinent place here to cite Sherlock
Holmes: Once you eliminate the impossible, whatever remains, no matter how
improbable, must be the truth. Leucopenia is syndrome of reduced number of
leukocytes and as eosinophils are major source of cytokines it is not quite
clear how reduced number of eosinophils can excrete so many cytokines to make
such devastation. Viral infections usually do not create state of leucopenia in
early stage, they all react on interferon, and usually one viral infection
suppress outer ones, but it is not case with Covid-19 at all: patients experienced
eruption of herpes and appearance of other chronic viral diseases.
Therefore according Holmes only remaining
possible tissue destructor can be the germ itself. What we could see there is
no known viral infection in existence able to produce such variety in symptoms
exposed on such scale from a single day mild fever to the next day lethal and
massive lung tissue necrosis. There are two possible culprits with good
fitting: a bacterium and a parasite. A parasite can be either some single cell
blood parasite akin to malaria either yeast, fungi or amoeba. Actually there
are two amoebas' infections that yield quite similar symptoms including
reduction of smell sense. Malaria has the same fluctuation in body temperature
in patients and attacks in similar intervals. Officially there is no cure for
those amoebas' infections except to wait for immune system to solve this
problem naturally. Most of those single cell parasites are anaerobic one fully
relied on ineffective Cori cycle which can be severely crippled by blockers of
proton pump, or H+ blocker medicaments. Those drugs with most
prominent generic Omeprazole can prevent creation of any acid in the body and
as the main by-product of the Cori cycle based cellular metabolism is
either acid or alcohol, but only yeasts create alcohol while all others have
more efficient Cory cycle based on acid synthesis, and thereby H+
blockers severely reduce Cori based metabolism of those parasites. This
campaign against wearing masks is unerringly similar to campaign of negating of
AIDS existence once upon a time with only one objective – to increase number of
infected! It may imply that this is an artificial contagion with major role to
damage global economy and cause poverty. The goal of anti-personal mines is not
to kill, but to cripple because one dead solder is buried on for two hours with
only two engaged solders, while wounded solder requires at least six extra ones
to transport him and 20 more solders to donate blood later. If this is really a
biological warfare then it is raised on higher more refined level: occasional
casualties filled with fear in between and then the conquered economy can be
instantly resuscitated and reused. The goal is clear to me, but this question
is out of the scope of this article because we do not know whether there is
some natural or unnatural extra source of infection occasionally activated or
the entire transmission is from human to human only.
Let us gather facts about Covi-19 together:
The disease is transmitting from
person to person via air from main sources mouth and nose. Pro: masks do help.
Contra: Elephants in Botswana were infected by water from nearby river. The
families possessing dishwashing machine has much lower chance to transmit
Covid-19 disease between family members. Smokers have better prognosis, small
children are sometimes negative on PCR test although exposing all symptoms.
The disease is caused by viral germ:
if this is true then interferon should be effective and antibiotics
ineffective, which is opposite to gathered facts approved in hospitals. The
viral diseases in their early stages always cause leukocytosis instead of
leucopenia. The immunity should sustain enough to prevent waves of infections
with short intervals, but this is also untrue - the level of supposed
antibodies drop too fast for a virus with possible reinfection. In many
children sick of Covid-19 PCR test remains negative. Available images obtained
from electronic microscope are rear and unconvincing - just small balls. And
what if it is parasite like Malaria because in elder patients we have hemolysis
followed by decrease of hemoglobin in blood in almost 50% of cases, which
completely matches the Malaria's clinical picture in some aspects and even more
anti-malaria medicaments are quite effective too. These symptoms resemble
very much to Altitude Sickness and in that case generic medicament Sildenafil
should help because Viagra reduces altitude sickness to the level that
alpinists can reach the tallest mountains without oxygen support at all.
There are also two funguses that can
cause similar symptoms: Histoplasmosis and Geomyces Destructans. It is
interesting that smoking is beneficial factor in Covid-19 infection giving much
better prognosis to smokers than non-smokers implying that antifungal properties
of tobacco may play significant role in prognosis of this allegedly viral
infection.
There is chance that this might be
also result of microwave injury. Some patients have swelling limbs full of
lymph that should be punctured out to prevent necrosis of skin. All the
symptoms including drop of iron and hemoglobin in blood are also symptoms of
exposure to microwave radiation. The birds dropping dead from sky in daylight
preceding wave of Covid-19 infection is an event uncannily similar to microwave
poisoning caused by microwave burst coming from above. This must involve little
green people into the plot, which is currently beyond the scope of this text.
If we apply Sherlock Holmes deduction to the
Covid-19 and we assume that there is no massive conspiracy among doctors then
we have a binary disease here, i.e. two pathogens conquering the body combined
in symbiosis. We know that symbiosis does exist in nature and in this
particular case they may stretch the human immune system on two fronts,
conveniently our immune system works badly in multitasking copping with two
sorts of germs simultaneously. The primary and necessary component is obviously
a Covid-19 virus that without second component yields only mild influenca
lasting for couple days only. But, the second infective component is able to
inflict severe damage to the lung tissue altogether with leucopenia and drop in
sedimentation implying that second component is most likely either bacterium or
parasite. This perfectly explains all symptoms combined. The second component
is not some opportunistic infection, this is second player genetically adjusted
to fight combined with the virus. First component is spreading by air and
second one by water, and both of them from person to person. So, the vaccine
must cover both pathogens. This also explains such easiness in passing from
specie to specie.
My best candidate for bacterium as cause of
Covid-19 is anaerobic Clostridium bacterium that has been found almost in every
specimen of lung tissues without any single exception, circumstantially proving
that these pneumonias are not caused by some random opportune infections as a
result of leucopenia.
THE MASKS AND THE PETS
Only what we have really effective in our fight
against Covid-19 contagions are masks. The wearing of masks is an altruistic
endeavor with major goal to protect others from us and this works only if we
all wear masks covering both mouth and nose simultaneously. I am not pretty
much amazed by the effectiveness of masks available on the market, but they
really reduce chance of infection about 100 times, or about 40dB. Available
scientific studies pay more attention to the size of the pathogen which is
really irrelevant. The only important fact is size of the initiating droplets
that may or may not contain pathogens. This droplet is best stopped by
hydrophilic fabric like cotton. This initial droplet is subverted to law of
gravitation and after about 2 meters of trajectory it is dried and transformed
into infective nanoparticle. Nanoparticle is moving erratically in accordance
with Brown motion.
The filtration of such dry nanoparticles is
complicate task requiring expensive mask. Let us analyze the content of
droplets and nanoparticles first: micro-droplets are consisted mainly from
water and residuum, and the residuum is consisted from mucus eventually
containing pathogen. Mucus is consisted from proteins, polysaccharides or
gelatin (i.e. collagen) in respects of bacteria, viruses and parasites. The
filtration of emitting droplets is simple and easily achievable by reduction of
their water via hydroscopic fiber. Then their solid residuum remains glued to
the fibers of the masks. The filtration of the incoming nanoparticles is more
complicate, but fairly attainable too - we just need some oily substance able
to bind those droplets at the exterior layer of the mask, some oily detergent,
even small concentration of one for manual dishwashing may help a lot. We
should bear in mind here that oily substances are also drying only slower and
that such musk has limited time of safe usage, but in case of detergent the
humidity from breath may keep outer layer susceptible to such nanoparticles
because detergent may dissolve both water and lipids. By these simple
alterations we may increase filtration for at least three more order of
magnitudes, from 10000 to 100000 times, i.e. to achieve attenuation of 80dB to
100dB.
There is also no necessity to use antibacterial
soaps for hands washing simply because the goal is to deactivate virus via
damaging of its lipid envelope which will be done by most of decent soaps.
One more time, the hygiene is only what we have
really effective including quarantine which one aspect is wearing mask, washing
hands and face: we all must wear masks and this is not some severe violation of
our personal rights because initial condition to have violated those rights is
to be alive: live and let live. Not wearing masks or improperly wearing them is
extremely rude and savage behavior and not an expression of the freedom at all.
Wearing masks are effective indeed. The Covid-19 damages lungs and kidneys and
best protection is not to be infected because Covid-19 reinfection is possible
and more frequently than we may assume. It seems that every subsequent
reinfection is more severe than previous one occurring in two months intervals
when herd immunity is weakened.
The fact that antibodies against Covid-19 have
limited retention in our blood limits the protective period of any incoming
vaccine and severely ruins our expectation that some neat task will cease
Covid-19 contagion instantly. We even do not know whether the only source is
transmission between humans or there is some extra source either natural or
artificial one. Natural one can be some animal species or artificial one
implying we are dealing with terrorism on grand scale.
The very good circumstantial evidence that there
is some sort of conspiracy related to Covid-19 contagion is this correlated and
synchronized action to assure people not to wear masks as useless and allegedly
duly enslaving act with only goal to spread Covid-19 infection. There is also
total neglecting the fact that pets like dogs and cats can spread Covid-19 too
despite the fact that Covid-19 is confirmed in pets by PCR tests. There is no
some specific warning about pets and even more there is missing trial whether
the pets can transmit the disease asymptomatically.
CONCLUSION
This text contains major directives how to make
vaccine either by more sophisticate method or by less sophisticate method and
also how to make much better masks. Sophisticate method is based on the
synthetic protein mimic the virus in counter sideband or by viruses selected
according their infrared signature, while less sophisticate is based on
aforementioned reciprocal theorem claiming that simple checking if the Covid-19
antibodies affects akin viruses then those viruses can be used for polyvalent
vaccine.
But, prior to the creation of vaccine we must be
doubtless whether we are dealing with virus, bacterium and parasite or
something combined...
There is also guidance how to make much better
masks, but this is not completely helpful if there is some extra channel of
infection beside our mouths and noses, like pets, birds, potable water, foot,
etc...
This is simplified version of genuine text
without references. If some journal wants to publish genuine text then it will
be supplied will all references. Some parts of this text are duly proven facts,
some parts are yet to become facts and some parts should be taken for granted
in this simplified text’s version although full set of references does exist
for genuine version of this text.
If you feel that this text of mine might be game changer in the vaccine production then please pour some money into this particular research by your generous donation:
